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The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and growth of tumors. A gene that has been coined “the guardian of the genome,” when inactivated, it can also play a role in the persistence, growth, and spread of a cancer that develops. The TP53 gene or its proteins are also referred to as tumor protein TP53, cellular tumor antigen TP53, phosphoprotein TP53, antigen NY-CO-13, or transformation-related protein 53....

Thromboembolism is the name for when a blood clot (thrombus) that forms in a blood vessel breaks loose, is carried by the bloodstream, and blocks another blood vessel. This is a dangerous condition that can affect multiple organs, causing organ damage and even death. As such, it requires immediate treatment. Knowing the signs of thromboembolism and who is at risk can help you better recognize when you or someone you love needs medical attention....

Recovery from transgender surgery—also called gender affirmation surgery or gender confirmation surgery—can vary from person to person. It will depend on the type of procedure you have and your overall health. This article looks at surgery follow-up, recovery timeline, coping strategies, and wound care. Surgery Follow-Up Your surgery follow-up will depend on your procedures. In general, transgender surgery can be divided into transfeminine and transmasculine surgeries. When to Seek Help...

Blurry vision and headache can occur at the same time for a variety of reasons. This may be a sign that your eyes are overtaxed or that they are changing. It could also indicate a health issue that isn’t specific to your eyes at all. Although headaches are rarely a medical emergency, you shouldn’t ignore a severe one. This article will discuss how different kinds of headaches can affect your eyes and vision....

Earwax, also called cerumen, is a substance made up of dead skin, oil, bacteria, trapped water, and hair. Wax protects the ear from water, dirt, insects, fungi, bacteria, and harmful objects. How much earwax is made, the color, and the consistency of it will vary from person to person. This article explores the purpose of earwax, the different types, as well as the causes and symptoms of earwax buildup. It will also look at earwax removal and when to reach out to a medical professional....

Treating diabetes depends on a few factors, including type and severity. Some people may be able to treat some diabetes with natural and alternative methods to medications. These are considered complementary and alternative methods or traditional medications for diabetes. Examples include increasing exercise and using specific herbal remedies for diabetes. Every case of diabetes is unique to the person experiencing it. This article can help you learn about natural and alternative methods for treating some diabetes types, but it’s crucial to consult your healthcare provider about any treatment options....

Alopecia areata is an autoimmune disorder characterized by the rapid onset of hair loss in a sharply defined area. The term alopecia areata literally means “patchy baldness,” and any hair-bearing skin can be affected (even eyebrows and eyelashes), with the most noticeable being the scalp and face. Although the condition attacks hair follicles, it doesn’t destroy them, so there is no scarring and hair will re-grow over time. Children, teens, and adults can be affected and genetics play a part in who develops it....

Angina (angina pectoris) is a type of chest pain that is caused by a lack of blood flow to your heart muscle. Angina is a symptom of coronary artery disease (CAD), a common kind of heart disease that affects approximately 1 in 13 U adults in the United States. CAD is the leading cause of death in the U.S. This article will highlight important statistics and facts you need to know about angina....

Apple cider vinegar has been used as an alternative therapy for decades with claims it can help to lower blood sugar, blood pressure, weight, inflammation, and more. There is minimal research around the health claims of apple cider vinegar—especially related to its effects on gout—but there are a few studies that support some of these claims. Here, we take a closer look at apple cider vinegar, gout, and health claims related to them....

If you have astigmatism, the cornea (the clear dome of the eye) or the lens that focuses rays on the light-sensitive retina at the back of the eye is shaped so that there can be competing focal points. You may have difficulty seeing clearly at any distance without corrective lenses. Refractive laser surgery can correct astigmatism by using a laser to reshape the cornea. Techniques include laser-assisted in situ keratomileusis (LASIK), photorefractive keratectomy (PRK), and small incision lenticule extraction (SMILE)....

Human immunodeficiency virus (HIV), is a sexually transmitted infection (STI) that affects around 1.2 million people in the United States. Medications are available to help control the virus and better ensure a long, healthy life. But to get treated, you need first to get tested. This is where at-home HIV tests can help. Available for purchase online and from many drugstores and pharmacies, these products allow people to test themselves in the privacy of their own homes....

Various tools are used to monitor cancer progression and treatment response. For some cancers, tumor marker blood tests, such as the CA 15-3 blood test, can be indicative of tumor changes. The cancer antigen 15-3 (CA 15-3) biomarker test is used to monitor breast cancer and its response to treatment. The CA 15-3 antigen is a protein released into the bloodstream by breast cancer, various other cancers, and even some benign (noncancerous) conditions....

Chemical burns—otherwise known as caustic burns—occur when the skin comes into contact with an acid, base, alkali, detergent, or solvent, or the fumes produced by these corrosive materials. They most commonly affect the eyes, face, arms, and legs, but can cause serious damage to the mouth and throat if a corrosive material is ingested. Fortunately, most chemical burns don’t do major damage to the skin. In fact, many are caused by common household or workplace materials and can be treated in outpatient settings—only about 5 percent of patients seeking emergency medical care for a chemical burn are admitted to the hospital....

Appendicitis is a common cause of abdominal pain that starts near the belly button and moves to the lower right abdominal region. Appendicitis affects 5% to 9% of people over the course of their lifetime. Appendicitis is most often an acute condition, which happens once and is treated with the removal of the appendix. However, when symptoms last for seven days or longer, or come and go for longer than that period, it is considered chronic....

Coconut oil has many benefits for hair. It is used to relieve dandruff, restore luster to dry and damaged hair, tame frizz, and protect hair against styling damage. It is safe to use on most hair types. Coconut oil is packed with fatty acids that can improve hair health. It is found in many shampoos, conditioners, styling gels, and other haircare products. You can also use coconut oil straight from the jar in the kitchen as a prewash treatment or conditioning mask....

Contact dermatitis is an itchy, blistering skin rash typically caused by skin’s direct contact with a substance. In the irritant type of contact dermatitis, the most frequent triggers are chemicals such as in soaps, bleach, dyes, and solvents. In allergic contact dermatitis, common allergens include nickel, adhesives, plants, cosmetics, and topical medications. Narrowing the list of things you think may be causing your rash can help your healthcare provider make a formal diagnosis and provide you with strategies for avoiding such a reaction in the future....

Crohn’s colitis is a type of Crohn’s disease, a form of inflammatory bowel disease (IBD). Several types of Crohn’s exist, and each one is distinguished by the part of the digestive tract it affects. With Crohn’s colitis, the colon (large intestine) is inflamed. Sometimes called granulomatous colitis, this condition accounts for 20% of all Crohn’s diagnoses. You can have Crohn’s colitis only or more than one type of Crohn’s at the same time....

There are many different types of obsessions and compulsions. But most of them can be grouped into four categories: checking, order and symmetry, contamination, and taboo thoughts. Read on to learn more about the most common types of obsessive-compulsive disorder (OCD), risk factors, diagnosis, and treatment. What Is Obsessive-Compulsive Disorder? Obsessive-compulsive disorder (OCD) is a common, long-lasting mental health condition that involves disruptive, unwanted obsessions and compulsions. Obsessions refer to thoughts, worries, urges, preoccupations, or mental images that are persistent, disruptive, and intrusive....

Diffuse large B-cell lymphoma (DLBCL) is a cancer of the B cells of the lymphatic system. B cells are responsible for producing antibodies, which are highly specific proteins that fight against bacterial and viral infections. When cancer develops in the B cells, it is called a B-cell lymphoma. B-cell lymphoma is a type of non-Hodgkin’s lymphoma. DLBCL is the most common type of lymphoma in the United States. This article will review the causes and symptoms of DLBCL, how it is diagnosed and treated, and its prognosis....

In a new study, researchers found that adults who started gender-affirming hormone therapy (GAHT) as teenagers had better mental health outcomes than those who started treatment later, or not at all. Key Takeaways Gender-affirming hormone therapy (GAHT) helps people align their bodies to better match their gender identity.Researchers found that transgender individuals who wanted GAHT suffered less from mental health issues if they started it in adolescence, rather than in adulthood or not at all....