Pneumonia and asthma are both respiratory diseases, but the link between them goes beyond the pulmonary system. Factors involved in asthma put you at risk for pneumonia, and vice versa.
Asthma is a chronic lung disease in which airways are constricted by inflammation and mucus buildup, which may be reversible. Pneumonia is a lung infection usually caused by viruses, bacteria, or fungi.
Understanding the connection between these two conditions is important for preventing complications.
How Asthma Leads to Pneumonia
If you have asthma, you’ve likely developed lung damage and permanent respiratory problems. This increased weakness makes you more susceptible to lung infections, including pneumonia.
According to research, your chances of developing pneumonia may also increase not only because you have asthma, but because of the medications you take to manage it.
Specifically, using inhaled steroids combined with a long-acting beta agonist (LABA) for asthma seems to make you almost twice as likely to develop serious pneumonia as someone who uses a LABA alone.
Studies have also found that people with asthma who take only inhaled corticosteroids may be 83% more likely to develop pneumonia than those who don’t.
It’s not clear why inhaled steroids increase pneumonia risk, but people who use oral steroids (such as for rheumatic diseases) have long been known to have an elevated infection risk, because these drugs dampen the immune response.
Symptoms
Shortness of breath, coughing, increased pulse, and a faster breathing rate are among the symptoms that characterize both asthma and pneumonia. However, the two conditions do have distinctive differences.
Stopping inhaled steroids could potentially be dangerous to your health. The possibility of illness and even death from severe asthma (status asthmaticus) is a significant risk.
Causes
There are four main causes of pneumonia, each of which results in different types of infection. Likewise, there are several types of asthma with a variety of possible causes.
Aside from these, environmental and lifestyle factors can play a significant role in the development of both asthma and pneumonia, as can other underlying health issues.
Unlike pneumonia, genetics plays a significant role in whether you develop asthma. In fact, having a parent with asthma makes you between 3 and 6 times more likely to develop it.
Family history of asthma
Childhood viral respiratory infection
Allergies
Obesity
Exposure to smoke, dust, air pollution, chemical fumes
Bacterial infection
Viral infection (such as the flu)
Aspiration (inhaling foreign object)
Fungal infection (most common with a compromised immune system)
However, you may have no asthma symptoms or may go through periods without symptoms until a trigger causes an asthma attack. Triggers vary from person to person and can range from allergens like pollen and dander to exercise or temporary respiratory illness.
Diagnosis
The process of diagnosing pneumonia differs significantly from that of diagnosing asthma.
Determining what type of pneumonia you have is essential to finding the right course of treatment.
Physical exam to check for breathing distress
Peak expiratory flow rate to measure how hard you exhale
Spirometry to determine airflow obstruction
Bronchodilation test to check response to asthma medication
Physical exam to check for fever, cough, shortness of breath
Complete blood count (CBC, to check for elevated white blood count)
Sputum, blood, nasal secretions, or saliva culture analysis
Imaging: chest X-ray, CT (computed tomography) scan, bronchoscopy
With asthma, the diagnosis is the first step. You will also need to determine the triggers that provoke an asthma attack in you.
Treatment
Asthma is a chronic illness that cannot be cured. It can be managed, though, and that is the goal of asthma treatment.
In contrast, pneumonia is an infection that should resolve with proper care and treatment, which depend on which type of infection you’re diagnosed with and the severity of the illness.
While asthma may increase the risk of pneumonia, which is often treated with antibiotics, asthma itself isn’t treated with antibiotics.
Avoid triggers
Maintenance medication (inhaled corticosteroids, long-acting beta-agonists)
Quick-relief (rescue inhaler) medications (short-acting beta-agonists, anticholinergics, oral steroids)
Immunotherapy (allergy shots)
Bronchial thermoplasty (targets smooth muscles in lungs) to prevent airways from constricting
Home care (rest, fluids, vitamins, humidifier)
Over-the-counter medication (fever reducer, pain reliever, expectorant)
Prescription medication (antibiotic, antiviral, or antifungal)
Hospital care (intravenous drugs, breathing treatments, supplemental oxygen, ventilator)
Removal of foreign object (in aspiration pneumonia)
Two Important Vaccinations
Vaccinations bolster your immune system’s ability to protect you from disease. The flu vaccine and pneumonia vaccine are important ones in your case.
Flu Vaccine
If you have asthma, you are more likely than people without asthma to get the seasonal flu. You’re also almost 6 times more likely to develop pneumonia as a complication of the flu.
The Centers for Disease Control and Prevention (CDC) says people with asthma should get a flu shot—and not the nasal spray vaccine—because the spray can exacerbate asthma symptoms.
Pneumonia Vaccine
Because of the increased pneumonia risk, if you have asthma and are over 18, the CDC also recommends getting a pneumonia (pneumococcal) vaccine called Pneumovax. It’s also recommended for anyone over 65 and those with a weak or suppressed immune system.
If you’re over 65 or have certain additional conditions, you may also need an a second pneumonia vaccine called Prevnar. Studies show that the two vaccines are more effective than either one alone.
Conditions that warrant the dual vaccination include:
- Cerebrospinal fluid leak (caused by tear or hole in the membranes surrounding brain or spinal cord)
- Cochlear implant (surgically implanted hearing device)
- Not having a functional spleen
- Congenital (at birth) or acquired immunodeficiency
- HIV (human immunodeficiency virus) infection
- Chronic renal (kidney) failure
- Nephrotic syndrome (a kidney problem most common in children)
- Leukemia (cancers of the blood) or lymphoma (cancer of the lymph system, which helps your body fight infections)
- Hodgkin’s disease (a type of lymphoma)
- Multiple myeloma (cancer of the plasma cells, a type of white blood cell)
- Other cancers (excluding skin cancer)
- Suppressed immune system (body lacks proper amount of white blood cells or antibodies)
- Organ transplant
A Word From Verywell
It’s important to understand both asthma and pneumonia and protect yourself from preventable respiratory infections, especially during flu season.
You should also become very familiar with how symptoms of the two differ so that, if you have asthma, you can spot those that aren’t typical of your condition and may signal an infection. That way, you can get treatment before serious complications arise.
Frequently Asked Questions
- Can asthma medication help with pneumonia?
- Researchers have found that two drugs used to treat asthma may help prevent certain types of pneumonia. Singulair (montelukast) and Accolate (zafirlukast) may help stop pneumonia from progressing, which could reduce fatalities due to complications from pneumonia.
- Learn More:
- What Is Singulair?
- Are people with asthma more likely to get pneumonia?
- Yes. People with asthma are susceptible to pneumonia. This may be due to inflammation related to asthma, or it could be related to changes in the body that take place as a result of asthma treatments.
- Learn More:
- How Asthma Is Treated
- Are you at greater risk for severe COVID if you have asthma?
- If you have moderate-to-severe or uncontrolled asthma, you’re more likely to be hospitalized if you contract COVID-19. If you begin to feel ill, you should talk to your doctor about early treatments that can help prevent COVID from becoming serious.
- Learn More:
- What to Know About Asthma and COVID-19
Researchers have found that two drugs used to treat asthma may help prevent certain types of pneumonia. Singulair (montelukast) and Accolate (zafirlukast) may help stop pneumonia from progressing, which could reduce fatalities due to complications from pneumonia.
Yes. People with asthma are susceptible to pneumonia. This may be due to inflammation related to asthma, or it could be related to changes in the body that take place as a result of asthma treatments.
If you have moderate-to-severe or uncontrolled asthma, you’re more likely to be hospitalized if you contract COVID-19. If you begin to feel ill, you should talk to your doctor about early treatments that can help prevent COVID from becoming serious.
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- U.S. Centers for Disease Control and Prevention. Flu vaccines for people with asthma.
- U.S. Centers for Disease Control and Prevention. Morbidity and mortality weekly report: Updated recommendations for prevention of invasive pneumococcal disease among adults unsing the 23-Valent pneumococcal polysaccharide vaccine (PPSV23).
- U.S. Centers for Disease Control and Prevention. Use of 13-Valent pneumococcal conjugate vaccine and 23-Valent pneumococcal polysaccharide vaccine among children aged 6–18 years with immunocompromising conditions: Recommendations of the Advisory Committee on Immunization Practices (ACIP).
- Cardani A, Boulton A, Kim TS, Braciale TJ. Alveolar macrophages prevent lethal influenza pneumonia by inhibiting infection of type-1 alveolar epithelial cells. Thomas PG, ed. PLoS Pathog. 2017;13(1):e1006140. doi:10.1371/journal.ppat.1006140
- Zaidi SR, Blakey JD. Why are people with asthma susceptible to pneumonia? A review of factors related to upper airway bacteria. Respirology. 2019;24(5):423-430. doi:10.1111/resp.13528
By Pat Bass, MD
Dr. Bass is a board-certified internist, pediatrician, and a Fellow of the American Academy of Pediatrics and the American College of Physicians.